The main focus of the Sanner Lab at Scripps Research in La Jolla is the development of computational methods for predicting, analyzing, visualizing and optimizing molecular interactions. We have contributed to the development of several widely used software tools, including MSMS for calculating molecular surfaces, AutoDock4 and AutoDockFR for docking small molecules into proteins, F2Dock for docking proteins and, most recently, AutoDock CrankPep, along with a variety of graphical user interfaces such as PMV, Vision, AutoDockTools, AutoGridFR, ADapt and WEWoS.
Latest news
- Nov 6, 2026 MSMS 2.6.2 released A robustness release: MSMS no longer crashes on very large or unusual inputs, merges duplicate atoms instead of stopping, and computes all surface components in parallel.
- Oct 14, 2026 New lab website The Sanner Lab has a new website, with downloads, documentation and tutorials for each of our software tools.
Software
Downloads, documentation and tutorials. Click a picture to open that tool’s page.
Methods
Dock linear and cyclic peptides 
Dock small molecules into flexible receptors 
Find ligand-binding pockets on proteins 
Compute molecular surfaces
User interfaces
Lab
Who we are.
Publications
Papers from the lab.